#Malk with vitamin r skin#

The linear multiple regression model showed 25(OH)D levels to be influenced by age, season of blood vitamin D levels assessment, and psoriasis duration. Patients with bullous diseases showed the lowest vitamin D mean values (18.2 ng/mL). Psoriatic patients had significantly lower serum levels of 25(OH)D (21.8 ng/mL) than healthy controls (34.3 ng/mL) (chi-square = 11.5 P =. Vitamin D levels were significantly different among the 3 groups (K = 151.284 P =. Anagraphical data, 25(OH)D blood levels, and seasons of vitamin D levels assessments were recorded for each group. To investigate the controversial association between psoriasis and vitamin D levels.įrom 2012 to 2014, 561 subjects were assessed, of which 170 had psoriasis, 51 had an autoimmune bullous, and 340 were healthy patients. Recent literature has focused on the association of psoriasis with lower than normal or highly deficient vitamin D blood levels. Seasonal variation was thus found to be substantial, and bi-seasonal measurements are vital in order to capture the sizable fluctuations in vitamin D status in this Nordic population. Furthermore, vitamin D supplement use was substantial and affected the median concentrations markedly, more so during spring than autumn. Among adults, women in general had higher median 25(OH)D concentrations than men.

A wide range of 25(OH)D concentrations were found in spring and autumn, with very low and very high values in both seasons. It was found that 86% of both adults and children were vitamin D-sufficient in either spring and or/autumn however, many had a spring concentration below 50 nmol/L. Seasonal variations in 25(OH)D concentrations were evaluated graphically and descriptively, and status according to age, sex, and supplement use was described. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by liquid chromatography mass spectrometry, and information on supplement use was assessed from questionnaires. A sub-sample of participants had blood samples taken monthly over a year. In this study, 3092 persons aged 2 to 69 years (2565 adults, 527 children) had blood drawn twice (spring and autumn) between 20. The aim of the present study was to describe vitamin D status and seasonal variation in the general Danish population. Results: Significant lower plasma 25(OH)D levels were found in control group (p The plasma vitamin D (25(OH)D) level of case and control subjects were examined using Enzyme Linked Immunosorbent Assay (ELISA). Methods: Fourty four psoriatic patients and 44 healthy control subjects’ DNA samples were obtained in this case control study and genotyped for A-1012G polymorphism by Polymerase Chain Reaction (PCR).

Objective: We aimed to investigate associations between plasma level of 25(OH)D and one VDR gene polymorphism (A-1012G) with psoriasis. It is possible that this polymorphism is different among psoriatic patients and healthy one particularly in Medan, Indonesia population. Vitamin D receptor polymorphism is one of the multiple polymorphisms that predispose individuals to several diseases. The Vitamin D receptors alongside with plasma vitamin D (25(OH)D) level have known to be related with psoriasis.

#Malk with vitamin r skin#

Background: Psoriasis is a chronic inflammation of the skin caused by combination of genetic, immune and environmental factors.